This musical adaptation follows Louise and her friend Thelma, who set out on a spontaneous weekend trip that takes a sudden turn after a violent confrontation with a stranger. As they leave the scene and begin to flee, their journey evolves into a cross-country escape shaped by increasing danger and limited options. Their friendship is tested and strengthened as they navigate a series of escalating consequences.

Starring Rachel Tucker and Amy Lennox, the production reimagines the original story with a score by Neko Case and a book by Callie Khouri. Directed by Trip Cullman, the musical frames the narrative through song and movement as the pair confront the realities of their situation.