Taking place during a scorching afternoon in the quaint Maynard, Texas, Laundry & Bourbon delves into the intertwined lives of two friends, folding laundry on Elizabeth's porch. As twilight approaches, the women relish sips of bourbon, exchanging intimate confidences and reminiscing about their experiences, romances, and aspirations. The arrival of Amy Lee, however, becomes the catalyst for chaos and upheaval.